SLC11A1
Reactivity: Human
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
SLC11A1 antibody can be used for detection of SLC11A1 by ELISA at 1:1562500. SLC11A1 antibody can be used for detection of SLC11A1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Handling Advice
As with any antibody avoid repeat freeze-thaw cycles.
Storage
4 °C/-20 °C
Storage Comment
For short periods of storage (days) store at 4 °C. For longer periods of storage, store SLC11A1 antibody at -20 °C.
Target
SLC11A1
(Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))
SLC11A1 antibody, NRAMP1 antibody, LSH antibody, NRAMP antibody, Bcg antibody, Itg antibody, Lsh antibody, Nramp1 antibody, Ity antibody, Nramp antibody, ity antibody, BCG antibody, solute carrier family 11 member 1 L homeolog antibody, solute carrier family 11 member 1 antibody, solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 antibody, slc11a1.L antibody, SLC11A1 antibody, Slc11a1 antibody
Background
SLC11A1 is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and is a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in its gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease.