Butyrylcholinesterase antibody

Catalog No. ABIN2462791

Product Details anti-Butyrylcholinesterase Antibody

Target: Butyrylcholinesterase (BCHE)

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Butyrylcholinesterase antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BCHE.

Application Details

Application Notes: BCHE antibody can be used for detection of BCHE by ELISA at 1:312500. BCHE antibody can be used for detection of BCHE by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store BCHE antibody at -20 °C.

Target Details for Butyrylcholinesterase

Target: Butyrylcholinesterase (BCHE)

Alternative Name: BCHE (BCHE Products)

Synonyms: che antibody, che1 antibody, bche antibody, cholinesterase antibody, CHE1 antibody, CHE2 antibody, E1 antibody, C730038G20Rik antibody, butyrylcholinesterase L homeolog antibody, butyrylcholinesterase antibody, bche.L antibody, bche antibody, BCHE antibody, Bche antibody

Background: Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.

Molecular Weight: 68 kDa

Gene ID: 590

NCBI Accession: NP_000046

UniProt: P06276

Pathways: Peptide Hormone Metabolism