CDT1 antibody

Catalog No. ABIN2462973

Product Details anti-CDT1 Antibody

Target: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDT1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CDT1.

Application Details

Application Notes: CDT1 antibody can be used for detection of CDT1 by ELISA at 1:62500. CDT1 antibody can be used for detection of CDT1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CDT1 antibody at -20 °C.

Target Details for CDT1

Target: CDT1 (Chromatin Licensing and DNA Replication Factor 1 (CDT1))

Alternative Name: CDT1 (CDT1 Products)

Synonyms: CDT1 antibody, fc37h07 antibody, im:7158083 antibody, wu:fc37h07 antibody, wu:fi38h09 antibody, xcdt1 antibody, DUP antibody, RIS2 antibody, 2610318F11Rik antibody, AW545653 antibody, C76791 antibody, Ris2 antibody, dup antibody, ris2 antibody, chromatin licensing and DNA replication factor 1 antibody, chromatin licensing and DNA replication factor 1 L homeolog antibody, CDT1 antibody, cdt1 antibody, Cdt1 antibody, cdt1.L antibody

Background: CDT1 cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. It binds DNA in a sequence-, strand-, and conformation-independent manner and is a potential oncogene.

Molecular Weight: 60 kDa

Gene ID: 81620

NCBI Accession: NP_112190

UniProt: Q9H211

Pathways: MAPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA