ST3GAL5 antibody

Catalog No. ABIN2462977

Product Details anti-ST3GAL5 Antibody

Target: ST3GAL5 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST3GAL5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ST3GAL5.

Application Details

Application Notes: ST3GAL5 antibody can be used for detection of ST3GAL5 by ELISA at 1:1562500. ST3GAL5 antibody can be used for detection of ST3GAL5 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ST3GAL5 antibody at -20 °C.

Target Details for ST3GAL5

Target: ST3GAL5 (ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5))

Alternative Name: ST3GAL5 (ST3GAL5 Products)

Synonyms: SATI antibody, SIAT9 antibody, SIATGM3S antibody, ST3GalV antibody, ST3GAL-V antibody, 3S-T antibody, Siat9 antibody, [a]2 antibody, ST3 beta-galactoside alpha-2,3-sialyltransferase 5 antibody, ST3GAL5 antibody, St3gal5 antibody

Background: Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. ST3GAL5 is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. It is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in its gene has been associated with Amish infantile epilepsy syndrome.Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus.

Molecular Weight: 48 kDa, 46 kDa

Gene ID: 8869

NCBI Accession: NP_003887

UniProt: Q6NZX4