NSDHL antibody

Catalog No. ABIN2463049

Product Details anti-NSDHL Antibody

Target: NSDHL (NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSDHL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NSDHL.

Application Details

Application Notes: NSDHL antibody can be used for detection of NSDHL by ELISA at 1:312500. NSDHL antibody can be used for detection of NSDHL by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NSDHL antibody at -20 °C.

Target Details for NSDHL

Target: NSDHL (NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL))

Alternative Name: NSDHL (NSDHL Products)

Synonyms: zgc:112474 antibody, H105E3 antibody, SDR31E1 antibody, XAP104 antibody, AI747449 antibody, Bpa antibody, Str antibody, NAD(P) dependent steroid dehydrogenase-like antibody, NAD(P) dependent steroid dehydrogenase-like L homeolog antibody, NSDHL antibody, nsdhl antibody, nsdhl.L antibody, Nsdhl antibody

Background: NSDHL is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in NSDHL gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males.The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.

Molecular Weight: 42 kDa

Gene ID: 50814

NCBI Accession: NP_057006

UniProt: Q15738