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PSMC3IP antibody

PSMC3IP Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2463083
  • Target See all PSMC3IP Antibodies
    PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
    Reactivity
    • 20
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    • 4
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    • 4
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    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    Human
    Host
    • 22
    • 1
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PSMC3IP antibody is un-conjugated
    Application
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC3IP.
    Top Product
    Discover our top product PSMC3IP Primary Antibody
  • Application Notes
    PSMC3IP antibody can be used for detection of PSMC3IP by ELISA at 1:62500. PSMC3IP antibody can be used for detection of PSMC3IP by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMC3IP antibody at -20 °C.
  • Target
    PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))
    Alternative Name
    PSMC3IP (PSMC3IP Products)
    Synonyms
    PSMC3IP antibody, Arabidopsis Hop2 homolog antibody, T6J4.9 antibody, T6J4_9 antibody, C79099 antibody, GT198 antibody, HOP2 antibody, Tbpip antibody, HUMGT198A antibody, ODG3 antibody, TBPIP antibody, Gt198 antibody, zgc:86785 antibody, PSMC3 interacting protein antibody, homologous-pairing protein 2 homolog antibody, Homologous-pairing protein 2 homolog antibody, homologous-pairing protein 2 homolog-like antibody, Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP) antibody, proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein antibody, PSMC3 interacting protein L homeolog antibody, PSMC3IP antibody, LOC726449 antibody, LOC100165513 antibody, hop2 antibody, psmc3ip antibody, LOC100633854 antibody, LOC100650062 antibody, LOC789362 antibody, AHP2 antibody, Psmc3ip antibody, psmc3ip.L antibody
    Background
    PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
    Molecular Weight
    25 kDa
    Gene ID
    29893
    NCBI Accession
    NP_057640
    UniProt
    Q9P2W1
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