CCT6B antibody

Catalog No. ABIN2463591

Product Details anti-CCT6B Antibody

Target: CCT6B (T-Complex Protein 1 Subunit zeta-2-Like (CCT6B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCT6B antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CCT6B.

Application Details

Application Notes: CCT6B antibody can be used for detection of CCT6B by ELISA at 1:312500. CCT6B antibody can be used for detection of CCT6B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CCT6B antibody at -20 °C.

Target Details for CCT6B

Target: CCT6B (T-Complex Protein 1 Subunit zeta-2-Like (CCT6B))

Alternative Name: CCT6B (CCT6B Products)

Synonyms: CCT-zeta-2 antibody, CCTZ-2 antibody, Cctz2 antibody, TCP-1-zeta-2 antibody, TSA303 antibody, CCTzeta-2 antibody, Cctz-2 antibody, chaperonin containing TCP1 subunit 6B antibody, T-complex protein 1 subunit zeta-2-like antibody, t-complex protein 1 subunit zeta-2-like antibody, chaperonin containing Tcp1, subunit 6b (zeta) antibody, CCT6B antibody, Cct6b antibody, LOC100445522 antibody, LOC100616822 antibody

Background: CCT6B is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Molecular Weight: 58 kDa

Gene ID: 10693

NCBI Accession: NP_006575

UniProt: Q92526