Ubiquilin 3 antibody

Catalog No. ABIN2463599

Product Details anti-Ubiquilin 3 Antibody

Target: Ubiquilin 3 (UBQLN3)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ubiquilin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBQLN3.

Application Details

Application Notes: UBQLN3 antibody can be used for detection of UBQLN3 by ELISA at 1:1562500. UBQLN3 antibody can be used for detection of UBQLN3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UBQLN3 antibody at -20 °C.

Target Details for Ubiquilin 3

Target: Ubiquilin 3 (UBQLN3)

Alternative Name: UBQLN3 (UBQLN3 Products)

Synonyms: TUP-1 antibody, 4933400K24Rik antibody, UBQLN3 antibody, ubiquilin 3 antibody, UBQLN3 antibody, Ubqln3 antibody

Background: UBQLN3 is an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. UBQLN3 is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis. This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.

Molecular Weight: 72 kDa

Gene ID: 50613

NCBI Accession: NP_059509

UniProt: Q9H347