Pellino 3 antibody

Catalog No. ABIN2463636

Product Details anti-Pellino 3 Antibody

Target: Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Pellino 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PELI3.

Application Details

Application Notes: PELI3 antibody can be used for detection of PELI3 by ELISA at 1:62500. PELI3 antibody can be used for detection of PELI3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PELI3 antibody at -20 °C.

Target Details for Pellino 3

Target: Pellino 3 (PELI3) (Pellino E3 Ubiquitin Protein Ligase Family Member 3 (PELI3))

Alternative Name: PELI3 (PELI3 Products)

Synonyms: 6030441F14Rik antibody, A930011L17 antibody, BC028931 antibody, RGD1305989 antibody, pellino 3 antibody, pellino E3 ubiquitin protein ligase family member 3 antibody, Peli3 antibody, PELI3 antibody

Background: Toll-like receptors (TLRs) and IL1R (IL1R1) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R.Toll-like receptors (TLRs, see MIM 603030) and IL1R (IL1R1, MIM 147810) are part of the innate immune response aimed at mobilizing defense mechanisms in response in infection or injury. Pellino proteins, such as PELI3, are intermediate components in the signaling cascades initiated by TLRs and IL1R (Jensen and Whitehead, 2003 [PubMed 12874243]).

Molecular Weight: 48 kDa

Gene ID: 246330

NCBI Accession: NP_001091980

Pathways: Toll-Like Receptors Cascades