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NR4A1 antibody (Internal Region)

NR4A1 Reactivity: Human, Horse, Monkey, Orang-Utan, Gibbon IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2469316
  • Target See all NR4A1 Antibodies
    NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
    Binding Specificity
    • 22
    • 16
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 82
    • 42
    • 39
    • 9
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Horse, Monkey, Orang-Utan, Gibbon
    Host
    • 82
    • 2
    • 2
    Rabbit
    Clonality
    • 81
    • 5
    Polyclonal
    Conjugate
    • 52
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR4A1 antibody is un-conjugated
    Application
    • 66
    • 31
    • 19
    • 15
    • 14
    • 14
    • 14
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    Immunohistochemistry (IHC)
    Specificity
    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    NR4A1 antibody was raised against a peptide located near the internal domain of NR4A1 (Human).
    Top Product
    Discover our top product NR4A1 Primary Antibody
  • Application Notes
    NR4A1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, 0.1 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies avoid freeze/thaw cycles.
    Storage
    4 °C/-80 °C
    Storage Comment
    NR4A1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
  • Target
    NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))
    Alternative Name
    NR4A1 (NR4A1 Products)
    Synonyms
    GFRP1 antibody, HMR antibody, N10 antibody, NAK-1 antibody, NGFIB antibody, NP10 antibody, NUR77 antibody, TR3 antibody, NGFI-B antibody, Gfrp antibody, Hbr-1 antibody, Hbr1 antibody, Hmr antibody, TIS1 antibody, nur77 antibody, Ngfi-b antibody, Nur77 antibody, nuclear receptor subfamily 4 group A member 1 antibody, nuclear receptor subfamily 4, group A, member 1 antibody, NR4A1 antibody, Nr4a1 antibody
    Background
    Nak1, a NR4 Nerve Growth Factor-Like receptor, has been shown to affect the hypothalamic-pituitary axis, neuronal differentiation, neuroendocrine regulation of adrenocortical function, and T-cell apoptosis. Nak1 also is known as nuclear receptor Tr3 and is similar to mouse Nur77 and rat NGFI-B. It is encoded by one of the immediate early genes (IEG) in response to nerve growth factor and other serum growth factors. Nak1 can bind to DNA as a monomer, homodimer, or heterodimer (with retinoid X receptors). Nak1 has been shown to inhibit vascular lesion formation and could serve as a novel target in the treatment of vascular diseases.
    Gene ID
    3164
    UniProt
    P22736
    Pathways
    Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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