TRPV2 antibody (N-Term)

Catalog No. ABIN2469502

Product Details anti-TRPV2 Antibody

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Binding Specificity: N-Term

Reactivity: Human, Horse, Monkey, Pig, Gorilla

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPV2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: TRPV2 antibody was raised against a peptide located in the N-Terminal domain of TRPV2 (Human).

Application Details

Application Notes: TRPV2 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200 - 1:400, and immunofluorescence starting at 1:200 - 1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: TRPV2 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for TRPV2

Target: TRPV2 (Transient Receptor Potential Cation Channel, Subfamily V, Member 2 (TRPV2))

Alternative Name: TRPV2 (TRPV2 Products)

Synonyms: TRPV2 antibody, VRL antibody, VRL-1 antibody, VRL1 antibody, Vrl1 antibody, GRC antibody, OTRPC2 antibody, transient receptor potential cation channel subfamily V member 2 antibody, transient receptor potential cation channel, subfamily V, member 2 antibody, TRPV2 antibody, LOC100540299 antibody, Trpv2 antibody

Background: Transient receptor potential vanilloid (TRPV) channels are widely expressed in both sensory and nonsensory cells. TRPV2, a member of transient receptor potential ion channels, responds to high-threshold noxious heat (with a threshold of approximately 52 degrees C), but neither to capsaicin nor to proton. TRPV2 transcripts are not restricted to the sensory nervous system, indicating that this channel may be activated by stimuli other than heat. It has been proposed that responses to noxious heat involve these related, but distinct, ion-channel subtypes that together detect a range of stimulus intensities.

Gene ID: 51393

UniProt: Q9Y5S1

Pathways: Regulation of Cell Size