FANCF antibody (Fanconi Anemia, Complementation Group F) (Internal Region)

Details for Product anti-FANCF Antibody No. ABIN2470175, Supplier: Log in to see
Antigen
  • FAF
  • A730016A17
  • RGD1561456
  • Fanconi anemia complementation group F L homeolog
  • Fanconi anemia, complementation group F
  • Fanconi anemia complementation group F
  • fancf.L
  • fancf
  • FANCF
  • Fancf
Epitope
Internal Region
12
11
5
4
3
2
2
1
1
Reactivity
Chimpanzee, Human
56
5
5
3
1
1
Host
Rabbit
31
20
5
Clonality
Polyclonal
Conjugate
This FANCF antibody is un-conjugated
3
3
3
2
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
49
44
9
7
5
4
1
Options
Supplier
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Immunogen FANCF antibody was raised against an internal amino acid sequence of FANCF (Human) near the internal region.
Purification Immunoaffinity Chromatography
Plasmids, Primers & others Plasmids, Primers & others FANCF products on genomics-online (e.g. as negative or positive controls)
Alternative Name FANCF (FANCF Antibody Abstract)
Background FANCF (also called Protein FACF or Fanconi Anemia Group F protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCF has also been implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCF belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. FANCF is found within the nucleus. Defects in FANCF are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level, it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.
Gene ID 2188
UniProt Q9NPI8
Application Notes FANCF antibody can be used in ELISA starting at 1:000 - 1:1000, and immunohistochemistry starting at 10 μg/mL.
Restrictions For Research Use only
Format Liquid
Buffer 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies avoid freeze/thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Store FANCF antibody at 4 °C or -20 °C.
Supplier Images
Immunohistochemistry (IHC) image for anti-Fanconi Anemia, Complementation Group F (FANCF) (Internal Region) antibody (ABIN2470175) anti-Fanconi Anemia, Complementation Group F (FANCF) (Internal Region) antibody
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