Glutamate Receptor 1 antibody (C-Term)

Catalog No. ABIN2473832

Product Details anti-Glutamate Receptor 1 Antibody

Target: Glutamate Receptor 1 (GLUR1)

Binding Specificity: C-Term

Reactivity: Human, Rat, Monkey, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Specificity: This antibody recognises the glutamate receptor 1 (also known as AMPA) which acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. This antibody linked to immobilized Protein A immunoprecipitates detergent-solubilized receptor from brain or transfected cells.

Cross-Reactivity: Hamster, Human, Monkey

Characteristics: Purified Ig

Purification: Purified

Immunogen: Synthetic peptide corresponding to the C terminal region of the native molecule conjugated to Bovine Serum Albumin.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GluR1 (GLUR1 Products)

Synonyms: GLUH1 antibody, GLUR1 antibody, GLURA antibody, GluA1 antibody, HBGR1 antibody, gluR-A antibody, 2900051M01Rik antibody, Glr-1 antibody, Glr1 antibody, GluR-A antibody, GluRA antibody, Glur-1 antibody, Glur1 antibody, HIPA1 antibody, gluR-K1 antibody, GRIA1 antibody, glur1 antibody, Gria1 antibody, glur1b antibody, gria1.2 antibody, sb:eu293 antibody, ZfGluR1a antibody, glur1a antibody, gria1.1 antibody, zfGRIA1[a] antibody, glutamate ionotropic receptor AMPA type subunit 1 antibody, glutamate receptor, ionotropic, AMPA1 (alpha 1) antibody, glutamate receptor, ionotropic, AMPA 1 antibody, glutamate receptor, ionotropic, AMPA 1 L homeolog antibody, GluR1 protein antibody, Glutamate receptor 1 antibody, glutamate receptor, ionotropic, AMPA 1b antibody, glutamate receptor, ionotropic, AMPA 1a antibody, GRIA1 antibody, Gria1 antibody, gria1 antibody, gria1.L antibody, glur1 antibody, glr-1 antibody, gria1b antibody, gria1a antibody

Background: Synonyms: GLUTAMATE RECEPTOR 1

Gene ID: 50592

UniProt: P19490

Pathways: PI3K-Akt Signaling