Lamin A/C antibody (LMNA)

Details for Product anti-LMNA Antibody No. ABIN2475293
Antigen
  • CDCD1
  • CDDC
  • CMD1A
  • CMT2B1
  • EMD2
  • FPL
  • FPLD
  • FPLD2
  • HGPS
  • IDC
  • LDP1
  • LFP
  • LGMD1B
  • LMN1
  • LMNC
  • LMNL1
  • PRO1
  • Dhe
  • 2459
  • 74/76
  • CG6944
  • D5
  • DM[[O]]
  • Dm
  • Dm(0)
  • Dm0
  • Dm1
  • Dm2
  • DmLamin
  • DmO
  • Dm[[0]]
  • Dm[[1]]
  • Dm[[2]]
  • Dm[[mit]]
  • Dm[[o]]
  • Dmel\\CG6944
  • Dmo
  • LAM
  • Lam Dm[[0]]
  • Lam(Dm0)
  • LamDm[[0]]
  • LamDm[[o]]
  • Lam[[Dm0]]
  • Lamin Dm[[0]]
  • jf27
  • l(2)04643
  • l(2)25Ec
  • l(2)gdh-7
  • l(2)gdh7
  • l(2)jf27
  • lam
  • lamDm0
  • lamDm[[0]]
  • lamin
  • lamin Dm0
  • lamin Dm[[0]]
  • misg
  • nlam
  • cb948
  • fk66d12
  • wu:fk66d12
  • lmna-A
  • fpl
  • idc
  • lfp
  • cddc
  • emd2
  • fpld
  • hgps
  • ldp1
  • lmn1
  • lmnc
  • pro1
  • cdcd1
  • cmd1a
  • cmt2b1
  • lgmd1b
  • Lamin-A
  • lamin-L(III)-like
  • lamin A/C
  • lamin A
  • Lamin
  • lamin A/C L homeolog
  • lamin-L(III)-like
  • LMNA
  • Lmna
  • Lam
  • lmna
  • lmna.L
  • LMINA
Reactivity
Human, Xenopus laevis
327
201
190
46
29
19
16
10
10
9
9
7
5
5
4
4
3
3
2
2
2
1
1
1
1
1
Host
Mouse
241
98
3
3
Clonality (Clone)
Monoclonal ()
Conjugate
This Lamin A/C antibody is un-conjugated
8
7
7
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
305
133
102
94
73
55
42
31
31
15
14
11
1
1
1
1
Options
Clone JOL2
Isotype IgG1
Cross-Reactivity Xenopus laevis
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others Lamin A/C products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name LAMIN A/C (LMNA Antibody Abstract)
Gene ID 4000
UniProt P02545
Pathways Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Product cited in: Tilgner, Wojciechowicz, Jahoda, Hutchison, Markiewicz: "Dynamic complexes of A-type lamins and emerin influence adipogenic capacity of the cell via nucleocytoplasmic distribution of beta-catenin." in: Journal of cell science, Vol. 122, Issue Pt 3, pp. 401-13, 2009 (PubMed).

Ivorra, Kubicek, González, Sanz-González, Alvarez-Barrientos, OConnor, Burke, Andrés: "A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C." in: Genes & development, Vol. 20, Issue 3, pp. 307-20, 2006 (PubMed).

Navarro, De Sandre-Giovannoli, Bernard, Boccaccio, Boyer, Geneviève, Hadj-Rabia, Gaudy-Marqueste, Smitt, Vabres, Faivre, Verloes, Van Essen, Flori, Hennekam, Beemer, Laurent, Le Merrer, Cau, Lévy: "Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy." in: Human molecular genetics, Vol. 13, Issue 20, pp. 2493-503, 2004 (PubMed).

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