P2RX7 antibody (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7) (Alexa Fluor 488)

Details for Product anti-P2RX7 Antibody No. ABIN2476003
Antigen
  • p2xr7
  • P2RX7
  • P2X7
  • AI467586
  • P2X(7)
  • P2X7R
  • p2x7
  • purinergic receptor P2X 7
  • purinergic receptor P2X, ligand-gated ion channel, 7
  • P2X purinoceptor 7
  • P2RX7
  • p2rx7
  • LOC100458463
  • P2rx7
Reactivity
Mouse (Murine)
95
59
39
4
4
3
3
3
2
2
Host
Rat
85
9
8
5
Clonality (Clone)
Monoclonal ()
Conjugate
This P2RX7 antibody is conjugated to Alexa Fluor 488
9
5
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
Application
Flow Cytometry (FACS)
71
45
37
13
13
13
8
6
2
1
1
Options
Immunogen A P2X7-expression construct and a final boost with P2X7-transfected HEK cells.
Clone Hano43
Isotype IgG2b
Plasmids, Primers & others Plasmids, Primers & others P2RX7 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name P2X7 (P2RX7 Antibody Abstract)
Gene ID 18439
UniProt Q9Z1M0
Pathways Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Product cited in: Adriouch, Bannas, Schwarz, Fliegert, Guse, Seman, Haag, Koch-Nolte: "ADP-ribosylation at R125 gates the P2X7 ion channel by presenting a covalent ligand to its nucleotide binding site." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 22, Issue 3, pp. 861-9, 2008 (PubMed).

Adriouch, Dubberke, Diessenbacher, Rassendren, Seman, Haag, Koch-Nolte: "Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 72-7, 2005 (PubMed).

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