PIK3CA antibody (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide) (Subunit alpha)

Details for Product anti-PIK3CA Antibody No. ABIN2476129
Antigen
  • PI3-kinase
  • PI3K-alpha
  • pi3-k
  • pi3k
  • 6330412C24Rik
  • caPI3K
  • p110
  • p110alpha
  • CLOVE
  • CWS5
  • MCAP
  • MCM
  • MCMTC
  • PI3K
  • p110-alpha
  • C-P3K
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
  • Phosphoinositide-3-kinase, catalytic, alpha polypeptide
  • phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
  • PIK3CA
  • GL50803_14855
  • pik3ca
  • Pik3ca
Epitope
Subunit alpha
24
19
15
15
11
11
11
8
7
4
4
3
3
2
2
2
2
2
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
149
94
49
1
Host
Goat
148
19
7
1
Clonality
Polyclonal
Conjugate
This PIK3CA antibody is un-conjugated
11
9
8
6
6
6
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
122
81
72
21
13
13
8
4
4
2
2
1
1
Options
Immunogen Synthetic peptide C-HQWLKDKNKGEIYD from the internal region of human PI3-kinase p110 subunit alpha (NP_006209.2).
Isotype IgG
Specificity This antibody specifically recognises human PI3-kinase p110 subunit alpha (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), otherwise known as PIK3CA, a member of the PI3/PI4-kinase family of lipid kinases, implicated in the regulation of signal transduction during cell growth. PI3-kinase is a heterodimer consisting of a p85 regulatory subunit and a p110 catalytic subunit, which itself is divided into isoforms p110alpha, p110beta, p110delta and p110gamma. Studies have shown that defects in p110alpha are associated with breast, colorectal and ovarian cancers.
Cross-Reactivity Cow (Bovine), Dog (Canine), Mouse (Murine), Rat (Rattus)
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others PIK3CA products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name pi-3 KINASE p110 SUBUNIT alpha (PIK3CA Antibody Abstract)
Background Synonyms: PIK3CA
Gene ID 5290
UniProt P42336
Pathways PI3K-Akt Signaling, RTK Signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Supplier Images
Image no. 1 for anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Subunit alpha) antibody (ABIN2476129) anti-Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA) (Subunit alpha) antibody
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