LCP2 antibody (Lymphocyte Cytosolic Protein 2 (SH2 Domain Containing Leukocyte Protein of 76kDa)) (AA 216-434)

Details for Product anti-LCP2 Antibody No. ABIN2476521
Antigen
  • AI323664
  • BB161688
  • SLP-76
  • SLP76
  • twm
  • Slp76
  • lymphocyte cytosolic protein 2
  • Lcp2
  • LCP2
Epitope
AA 216-434
24
24
8
6
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine)
142
90
60
10
Host
Mouse
115
23
7
Clonality (Clone)
Monoclonal ()
Conjugate
This LCP2 antibody is un-conjugated
4
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP), Western Blotting (WB)
116
41
36
28
15
8
8
7
2
1
1
Options
Immunogen A fusion protein corresponding to amino acids 216-434 of human SLP-76
Clone SLP-76-03
Isotype IgG2b
Cross-Reactivity Mouse (Murine), Pig (Porcine)
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others LCP2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name SLP-76 (LCP2 Antibody Abstract)
Gene ID 3937
UniProt Q13094
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Product cited in: Brockmeyer, Paster, Pepper, Tan, Trudgian, McGowan, Fu, Gascoigne, Acuto, Salek: "T cell receptor (TCR)-induced tyrosine phosphorylation dynamics identifies THEMIS as a new TCR signalosome component." in: The Journal of biological chemistry, Vol. 286, Issue 9, pp. 7535-47, 2011 (PubMed).

Di Bartolo, Montagne, Salek, Jungwirth, Carrette, Fourtane, Sol-Foulon, Michel, Schwartz, Lehmann, Acuto: "A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76." in: The Journal of experimental medicine, Vol. 204, Issue 3, pp. 681-91, 2007 (PubMed).

Bonilla, Fujita, Pivniouk, Chan, Geha: "Adapter proteins SLP-76 and BLNK both are expressed by murine macrophages and are linked to signaling via Fcgamma receptors I and II/III." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 4, pp. 1725-30, 2000 (PubMed).

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