DIABLO antibody (Second Mitochondria-Derived Activator of Caspase) (AA 225-239)

Details for Product anti-DIABLO Antibody No. ABIN2476525
Antigen
  • smac
  • smac3
  • diablo-s
  • 0610041G12Rik
  • 1700006L01Rik
  • AU040403
  • Smac
  • DFNA64
  • SMAC
  • DBO
  • XSmac
  • diablo, IAP-binding mitochondrial protein
  • diablo IAP-binding mitochondrial protein
  • diablo, IAP-binding mitochondrial protein L homeolog
  • diablo
  • Diablo
  • DIABLO
  • diablo.L
Epitope
AA 225-239, C-Term
28
17
11
11
8
6
4
4
3
2
2
2
2
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
184
72
58
4
3
2
2
2
2
1
1
Host
Rabbit
158
33
4
1
Clonality
Polyclonal
Conjugate
This DIABLO antibody is un-conjugated
5
3
3
3
3
3
3
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
163
77
62
40
24
14
10
8
8
5
4
4
2
2
2
1
1
1
1
Options
Immunogen Synthetic peptide corresponding to amino acids 225-239 of human Smac/DIABLO
Isotype IgG
Specificity This antibody recognises the C-terminal region of human Smac/DIABLO. Inhibitors of apoptosis proteins (IAP's) block cell death by caspase inhibition. X-linked inhibitor of apoptosis (XIAP) is a member of the IAP family. Smac/DIABLO is expressed in a variety of tissues and has been identified as a negative regulator of XIAP.
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others DIABLO products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name SMAC/DIABLO (DIABLO Antibody Abstract)
Gene ID 56616
UniProt Q9NR28
Pathways Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Supplier Images
Image no. 1 for anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 225-239), (C-Term) antibody (ABIN2476525) anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (AA 225-239), (C-Term) antibody
Product cited in: Verhagen, Coulson, Vaux: "Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs." in: Genome biology, Vol. 2, Issue 7, pp. REVIEWS3009, 2001 (PubMed).

Did you look for something else?