SOCS3 antibody (Suppressor of Cytokine Signaling 3)

Details for Product anti-SOCS3 Antibody No. ABIN2476543
Antigen
  • socs3
  • fj09e12
  • zgc:56537
  • wu:fj09e12
  • MGC64393
  • MGC75749
  • xsocs3
  • MGC81248
  • atod4
  • cis3
  • cish3
  • socs-3
  • ssi-3
  • ssi3
  • SOCS3
  • ATOD4
  • CIS3
  • Cish3
  • SOCS-3
  • SSI-3
  • SSI3
  • Cis3
  • EF-10
  • Ef10
  • Ssi3
  • Socs-3
  • Ssi-3
  • suppressor of cytokine signaling 3a
  • suppressor of cytokine signaling 3 S homeolog
  • suppressor of cytokine signaling 3
  • suppressor of cytokine signaling 3 L homeolog
  • socs3a
  • socs3.S
  • socs3
  • socs3.L
  • SOCS3
  • Socs3
Reactivity
Human
136
61
46
4
4
4
4
3
1
1
1
1
Host
Mouse
88
71
7
Clonality (Clone)
Monoclonal ()
Conjugate
This SOCS3 antibody is un-conjugated
14
7
3
2
2
2
2
2
2
1
1
1
Application
ELISA, Western Blotting (WB)
138
64
56
33
25
21
8
7
6
3
2
1
1
1
Options
Clone SO1
Isotype IgG2b
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others SOCS3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name SOCS-3 (SOCS3 Antibody Abstract)
Background Synonyms: SUPPRESSOR OF CYTOKINE SIGNALING 3
Gene ID 9021
UniProt O14543
Pathways JAK-STAT Signaling, Response to Growth Hormone Stimulus, Hepatitis C
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Product cited in: Lang, Pauleau, Parganas, Takahashi, Mages, Ihle, Rutschman, Murray: "SOCS3 regulates the plasticity of gp130 signaling." in: Nature immunology, Vol. 4, Issue 6, pp. 546-50, 2003 (PubMed).

Lehmann, Schmitz, Weissenbach, Sobota, Hortner, Friederichs, Behrmann, Tsiaris, Sasaki, Schneider-Mergener, Yoshimura, Neel, Heinrich, Schaper: "SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130." in: The Journal of biological chemistry, Vol. 278, Issue 1, pp. 661-71, 2002 (PubMed).

Suzuki, Hanada, Mitsuyama, Yoshida, Kamizono, Hoshino, Kubo, Yamashita, Okabe, Takeda, Akira, Matsumoto, Toyonaga, Sata, Yoshimura: "CIS3/SOCS3/SSI3 plays a negative regulatory role in STAT3 activation and intestinal inflammation." in: The Journal of experimental medicine, Vol. 193, Issue 4, pp. 471-81, 2001 (PubMed).

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