SNCAIP antibody (Synuclein, alpha Interacting Protein)

Details for Product anti-SNCAIP Antibody No. ABIN2476664
Antigen
  • sncaip
  • MGC88953
  • SNCAIP
  • LOC100221074
  • SYPH1
  • Sph1
  • Syph1
  • 2810407O15Rik
  • 4933427B05Rik
  • BB104594
  • synuclein alpha interacting protein
  • synuclein, alpha interacting protein
  • synuclein, alpha interacting protein (synphilin)
  • SNCAIP
  • sncaip
  • Sncaip
Reactivity
Human
73
37
19
1
1
1
Host
Goat
66
5
4
Clonality
Polyclonal
Conjugate
This SNCAIP antibody is un-conjugated
3
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
50
31
23
13
8
1
1
1
1
Options
Immunogen Peptide 829SLELNGEKDKDKGRTLQRT847
Isotype IgG
Specificity This antibody recognises synphilin-1, a cytoplasmic protein which associates with alpha-synuclein in vivo. Alpha-Synuclein is a major component of lewy bodies in patients with sporadic Parkinson's disease (PD) and mutations of alpha-synuclein are involved in familial forms of PD. Reports suggest that synphilin-1 may play a role in lewy body formation in association with alpha synuclein.
Characteristics Serum
Plasmids, Primers & others Plasmids, Primers & others SNCAIP products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name SYNPHILIN 1 (SNCAIP Antibody Abstract)
Gene ID 9627
UniProt Q9Y6H5
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Product cited in: Büttner, Delay, Franssens, Bammens, Ruli, Zaunschirm, de Oliveira, Outeiro, Madeo, Buée, Galas, Winderickx: "Synphilin-1 enhances ?-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner." in: PLoS ONE, Vol. 5, Issue 10, pp. e13700, 2010 (PubMed).

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