TSH receptor antibody (Thyroid Stimulating Hormone Receptor)

Details for Product anti-TSHR Antibody No. ABIN2476797
Antigen
  • CHNG1
  • LGR3
  • hTSHR-I
  • AI481368
  • hypothroid
  • hyt
  • pet
  • TSHRA
  • TSH-R
  • thyroid stimulating hormone receptor
  • tshr
  • TSHR
  • Tshr
Reactivity
Human
166
70
60
8
7
7
6
6
5
5
2
1
1
Host
Mouse
131
34
7
Clonality (Clone)
Monoclonal ()
Conjugate
This TSH receptor antibody is un-conjugated
8
7
7
4
4
4
4
4
4
3
3
3
3
3
2
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
73
43
41
40
38
36
20
10
7
5
3
2
2
1
Options
Clone 2C11
Isotype IgG1
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others TSH receptor products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name THYROID STIMULATING HORMONE RECEPTOR (TSHR Antibody Abstract)
Background Synonyms: THYROTROPIN RECEPTOR
Gene ID 7253
UniProt P16473
Pathways Thyroid Hormone Synthesis
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Product cited in: Neumann, Krause, Claus, Paschke: "Structural determinants for g protein activation and selectivity in the second intracellular loop of the thyrotropin receptor." in: Endocrinology, Vol. 146, Issue 1, pp. 477-85, 2004 (PubMed).

Chazenbalk, Pichurin, Chen, Latrofa, Johnstone, McLachlan, Rapoport: "Thyroid-stimulating autoantibodies in Graves disease preferentially recognize the free A subunit, not the thyrotropin holoreceptor." in: The Journal of clinical investigation, Vol. 110, Issue 2, pp. 209-17, 2002 (PubMed).

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