Tumor Necrosis Factor antibody (TNF)

Details for Product anti-TNF Antibody No. ABIN2476867
Antigen
  • DIF
  • TNF-alpha
  • TNFA
  • TNFSF2
  • RATTNF
  • Tnfa
  • tnf
  • TNF-a
  • TNFalpha
  • Tnfsf1a
  • TNFa
  • cTNF
  • Tnf-alpha
  • tnfa-like
  • TNF-ALPHA
  • dif
  • tnfa
  • xtnf
  • tnfsf2
  • tnf-alpha
  • Cachectin
  • tumor necrosis factor
  • tumor necrosis factor b (TNF superfamily, member 2)
  • tumor necrosis factor alpha
  • tumor necrosis factor a (TNF superfamily, member 2)
  • TNF
  • Tnf
  • tnf
  • tnfb
  • tnf-alpha
  • LOC103694380
  • tnfa
Reactivity
Pig (Porcine)
995
386
316
137
132
116
115
56
50
40
26
18
17
7
6
6
5
4
4
3
3
3
2
2
1
1
1
1
Host
Mouse
730
496
78
48
10
6
6
5
2
2
2
2
Clonality (Clone)
Monoclonal ()
Conjugate
This Tumor Necrosis Factor antibody is un-conjugated
160
71
46
38
31
20
14
11
11
11
11
11
11
11
11
11
11
11
11
11
8
7
7
7
7
7
2
2
2
2
2
2
1
Application
Functional Studies (Func), ELISA, Western Blotting (WB)
659
630
464
425
289
128
118
86
75
69
63
59
42
30
26
19
18
16
14
10
9
8
7
6
6
6
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
Options
Immunogen Recombinant porcine TNF alpha
Clone 6E10
Isotype IgG1
Specificity This antibody is specific for porcine tumour necrosis factor alpha (TNF alpha). The antibody recognises both native and recombinant TNF alpha. TNF alpha is expressed by a range of cells including macrophages and monocytes, and is an important mediator of the porcine inflammatory response. Clone 6E10 is reported to neutralise the effects of porcine TNF alpha in in vitro cytotoxicity assays using WEHI 164 clone 13 murine fibrosarcoma cells, see Su, X. et al. for details.
Characteristics Purified IgG
Plasmids, Primers & others Plasmids, Primers & others Tumor Necrosis Factor products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TNF alpha (TNF Antibody Abstract)
Gene ID 397086
UniProt P23563
Pathways NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Preservative Without preservative
Product cited in: Zelnickova, Faldyna, Stepanova, Ondracek, Kovaru: "Intracellular cytokine detection by flow cytometry in pigs: fixation, permeabilization and cell surface staining." in: Journal of immunological methods, Vol. 327, Issue 1-2, pp. 18-29, 2007 (PubMed).

Did you look for something else?