NR4A1 antibody (Nuclear Receptor Subfamily 4, Group A, Member 1) (Internal Region)

Details for Product anti-NR4A1 Antibody No. ABIN2476909
Antigen
  • GFRP1
  • HMR
  • N10
  • NAK-1
  • NGFIB
  • NP10
  • NUR77
  • TR3
  • NGFI-B
  • Gfrp
  • Hbr-1
  • Hbr1
  • Hmr
  • TIS1
  • nur77
  • Ngfi-b
  • Nur77
  • nuclear receptor subfamily 4 group A member 1
  • nuclear receptor subfamily 4, group A, member 1
  • NR4A1
  • Nr4a1
Epitope
Internal Region
43
20
15
15
14
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
189
77
73
12
10
10
9
7
7
4
3
2
1
1
1
1
Host
Goat
179
8
7
Clonality
Polyclonal
Conjugate
This NR4A1 antibody is un-conjugated
10
6
6
6
5
5
5
5
5
5
5
5
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
115
75
39
37
21
14
9
6
5
3
3
2
1
1
Options
Immunogen Synthetic peptide sequence C-GRLPSKPKQPPDAS from the internal region of TR3 orphan receptor (NP_002126.2, NP_775180.1).
Isotype IgG
Specificity This antibody specifically recognises human TR3 orphan receptor, otherwise known as NUR77, an immediate-early orphan nuclear receptor, and member of the nuclear receptor hormone family, encoded by the NR4A1 gene. TR3 orphan receptor plays a role in the mediation of macrophage inflammatory responses, and in apoptosis and cell proliferation, through the binding to a variety of response elements. TR3 orphan receptor has been shown to bind to the anti-apoptotic protein Bcl-2, and can be induced by both physiological and physical stress-related stimuli, including tumour necrosis factor (TNF), inflammatory cytokines and magnetic fields. This antibody is expected to recognise isoform a of TR3 orphan receptor.
Cross-Reactivity Dog (Canine), Mouse (Murine), Rat (Rattus)
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others NR4A1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TR3 ORPHAN RECEPTOR (NR4A1 Antibody Abstract)
Background Synonyms: NUR77/NR4A1
Gene ID 3164
UniProt P22736
Pathways Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Supplier Images
Image no. 1 for anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (Internal Region) antibody (ABIN2476909) anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) (Internal Region) antibody
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