ULK2 antibody (Unc-51 Like Kinase 2 (C. Elegans)) (AA 370-382)

Details for Product anti-ULK2 Antibody No. ABIN2477034
Antigen
  • ULK2
  • ATG1B
  • Unc51.2
  • A830085I22Rik
  • AU015340
  • mKIAA0623
  • unc-51 like autophagy activating kinase 2
  • unc-51 like kinase 2
  • ULK2
  • Ulk2
  • ulk2
Epitope
AA 370-382
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24
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1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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39
28
Host
Rabbit
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24
Clonality
Polyclonal
Conjugate
This ULK2 antibody is un-conjugated
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Application
Western Blotting (WB)
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87
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Options
Immunogen KLH conjugated synthetic peptide corresponding to amino acids 370-382 of mouse Ulk2. The corresponding sequence differs by two amino acids in rat and three amino acids in human.
Isotype IgG
Specificity This antibody specifically recognises mouse Ulk2 (Serine/threonine-protein kinase Ulk2), otherwise known as Unc-51-like kinase 2, a widely expressed mammalian Atg1 homologue and member of the protein kinase superfamily, which shares structural similarity with a serine/threonine kinase found in C. elegans, known to be involved in axonal elongation. Studies have shown that murine Ulk2 and closely-related Ulk1, localize to autophagic isolation membranes under starvation conditions, and that the binding of Atg13 (Autophagy-related protein 13) to Ulk1 and Ulk2, stabilizes and activates them, and facilitates the phosphorylation of FIP200, a multifunctional protein involved in cell migration, proliferation, apoptosis, and tumor suppression.
Cross-Reactivity Human, Rat (Rattus)
Characteristics Purified IgG
Purification Purified
Plasmids, Primers & others Plasmids, Primers & others ULK2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name ULK2 (ULK2 Antibody Abstract)
Background Synonyms: UNC-51-LIKE KINASE 2
Gene ID 29869
UniProt Q9QY01
Pathways Regulation of Cell Size
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
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