ULK2 antibody (AA 370-382)

Catalog No. ABIN2477034

Product Details anti-ULK2 Antibody

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Binding Specificity: AA 370-382

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULK2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody specifically recognises mouse Ulk2 (Serine/threonine-protein kinase Ulk2), otherwise known as Unc-51-like kinase 2, a widely expressed mammalian Atg1 homologue and member of the protein kinase superfamily, which shares structural similarity with a serine/threonine kinase found in C. elegans, known to be involved in axonal elongation. Studies have shown that murine Ulk2 and closely-related Ulk1, localize to autophagic isolation membranes under starvation conditions, and that the binding of Atg13 (Autophagy-related protein 13) to Ulk1 and Ulk2, stabilizes and activates them, and facilitates the phosphorylation of FIP200, a multifunctional protein involved in cell migration, proliferation, apoptosis, and tumor suppression.

Cross-Reactivity: Human, Rat (Rattus)

Characteristics: Purified IgG

Purification: Purified

Immunogen: KLH conjugated synthetic peptide corresponding to amino acids 370-382 of mouse Ulk2. The corresponding sequence differs by two amino acids in rat and three amino acids in human.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Target Details for ULK2

Target: ULK2 (Unc-51 Like Kinase 2 (ULK2))

Alternative Name: ULK2 (ULK2 Products)

Synonyms: ULK2 antibody, ATG1B antibody, Unc51.2 antibody, A830085I22Rik antibody, AU015340 antibody, mKIAA0623 antibody, unc-51 like autophagy activating kinase 2 antibody, unc-51 like kinase 2 antibody, ULK2 antibody, Ulk2 antibody, ulk2 antibody

Background: Synonyms: UNC-51-LIKE KINASE 2

Gene ID: 29869

UniProt: Q9QY01

Pathways: Regulation of Cell Size, Autophagy