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ABCC9 antibody (AA 1505-1546) (Alkaline Phosphatase (AP))

ABCC9 Reactivity: Mouse WB, IHC, ICC, IF Host: Mouse Monoclonal S319A-14 Alkaline Phosphatase (AP)
Catalog No. ABIN2482976
  • Target See all ABCC9 Antibodies
    ABCC9 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 9 (ABCC9))
    Binding Specificity
    • 14
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1505-1546
    Reactivity
    • 37
    • 34
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 36
    • 15
    • 1
    Mouse
    Clonality
    • 37
    • 15
    Monoclonal
    Conjugate
    • 18
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABCC9 antibody is conjugated to Alkaline Phosphatase (AP)
    Application
    • 35
    • 25
    • 19
    • 15
    • 15
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    Detects ~120 kDa. Does not cross-react with SUR2B.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 1505-1546 (SSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK, cytoplasmic C-terminus) of mouse SUR2A
    Clone
    S319A-14
    Isotype
    IgG2a
    Top Product
    Discover our top product ABCC9 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2482976 was sufficient for detection of SUR2A in 20 μg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    ABCC9 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 9 (ABCC9))
    Alternative Name
    SUR2A (ABCC9 Products)
    Synonyms
    SUR2B antibody, DDBDRAFT_0215814 antibody, DDBDRAFT_0216237 antibody, DDB_0215814 antibody, DDB_0216237 antibody, si:dkey-183c2.3 antibody, sur2 antibody, ABC37 antibody, ATFB12 antibody, CANTU antibody, CMD1O antibody, SUR2 antibody, SUR2A antibody, AI414027 antibody, AI449286 antibody, Sur2 antibody, ABCC9 antibody, ATP binding cassette subfamily C member 9 antibody, ATP-binding cassette sub-family C member 8 antibody, ABC transporter C family protein antibody, ATP-binding cassette sub-family C member 9 antibody, ATP-binding cassette, sub-family C (CFTR/MRP), member 9 antibody, ABCC9 antibody, LOC581821 antibody, abcC9 antibody, LOC100470981 antibody, abcc9 antibody, Abcc9 antibody
    Background
    Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6.x (6.1 and 6.2) (1). The association of four Kir6.x and four SUR subunits form an ion conducting channel commonly referred to as the KATP channel. The primary function of the sulfonylurea receptor is to sense intracellular levels of the nucleotides ATP and ADP and in response facilitate the open or closing its associated Kir6.x potassium channel. Hence the KATP channel monitors the energy balance within the cell (2).
    Gene ID
    20928
    NCBI Accession
    NP_001038185
    UniProt
    P70170
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