TRPM7 antibody (Transient Receptor Potential Cation Channel, Subfamily M, Member 7) (AA 1817-1863) (Atto 655)

Details for Product anti-TRPM7 Antibody No. ABIN2483109
Antigen
  • cb495
  • TRPM7
  • chak
  • chak1
  • ltrpc7
  • trp-plik
  • ALSPDC
  • CHAK
  • CHAK1
  • LTRPC7
  • TRP-PLIK
  • 2310022G15Rik
  • 4833414K03Rik
  • 5033407O22Rik
  • LTrpC-7
  • Ltpr7
  • Ltrpc7
  • TRPPLIK
  • Chak
  • Trp-plik
  • transient receptor potential cation channel subfamily M member 7
  • transient receptor potential cation channel, subfamily M, member 7
  • TRPM7
  • trpm7
  • Trpm7
Epitope
AA 1817-1863
28
25
15
13
11
10
8
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
127
71
68
2
1
1
1
Host
Mouse
104
34
8
3
Clonality (Clone)
Monoclonal ()
Conjugate
This TRPM7 antibody is conjugated to Atto 655
8
7
7
6
6
6
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Antibody Array (AA), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
108
91
61
30
26
23
18
13
12
3
2
2
2
1
1
1
Options
Immunogen Fusion protein amino acids 1817-1863 (C- terminus) of mouse TrpM7
Clone S74-25
Isotype IgG1
Specificity Detects ~220 kDa in extracts of cells transiently transfected with TrpM7. No cross-reactivity against TrpM6.
Purification Protein G Purified
Plasmids, Primers & others Plasmids, Primers & others TRPM7 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name TRPM7 (TRPM7 Antibody Abstract)
Background TRPs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants (1, 2).
Gene ID 58800
NCBI Accession NP_001157797
UniProt Q923J1
Application Notes
  • WB (1:1000)
  • IHC (1:1000)
  • ICC/IF (1:100)
  • optimal dilutions for assays should be determined by the user.
Comment

1 μg/ml of ABIN2483109 was sufficient for detection of TrpM7 in 10 μg of COS cell lysate transiently transfected with TprM7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Supplier Images
Image no. 1 for anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Atto 655) (ABIN2483109) Immunohistochemistry analysis using Mouse Anti-TrpM7 Monoclonal Antibody, Clone S74-2...
Image no. 2 for anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Atto 655) (ABIN2483109) Western Blot analysis of Human Cell lysates showing detection of TrpM7 protein using ...
Image no. 3 for anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) (AA 1817-1863) antibody (Atto 655) (ABIN2483109) Immunohistochemistry analysis using Mouse Anti-TrpM7 Monoclonal Antibody, Clone S74-2...
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