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KCNQ1 antibody (AA 2-101) (PE)

KCNQ1 Reactivity: Human WB, IHC, IP, IF, ICC, AA Host: Mouse Monoclonal N37A-10 (Formerly S37A-10) PE
Catalog No. ABIN2483170
  • Target See all KCNQ1 Antibodies
    KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
    Binding Specificity
    • 15
    • 12
    • 10
    • 8
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-101
    Reactivity
    • 59
    • 34
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 15
    • 1
    • 1
    Mouse
    Clonality
    • 60
    • 15
    Monoclonal
    Conjugate
    • 30
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNQ1 antibody is conjugated to PE
    Application
    • 67
    • 27
    • 19
    • 14
    • 13
    • 13
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)
    Specificity
    Detects ~75 kDa.
    Cross-Reactivity
    Hamster, Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 2-101 of human KCNQ1
    Clone
    N37A-10 (Formerly S37A-10)
    Isotype
    IgG1
    Top Product
    Discover our top product KCNQ1 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2483170 was sufficient for detection of KCNQ1 in 10 μg of COS-1 cell lysate transiently expressing KCNQ1 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
    Alternative Name
    KCNQ1 (KCNQ1 Products)
    Synonyms
    ATFB1 antibody, ATFB3 antibody, JLNS1 antibody, KCNA8 antibody, KCNA9 antibody, KVLQT1 antibody, Kv1.9 antibody, Kv7.1 antibody, LQT antibody, LQT1 antibody, RWS antibody, SQT2 antibody, WRS antibody, CG12215 antibody, CG12915 antibody, CG33135 antibody, DKCNQ antibody, Dmel\\CG33135 antibody, dKCNQ antibody, kcnq1 antibody, KCNQ1 antibody, kqt-3 antibody, kv7.1 antibody, Kvlqt1 antibody, KvLQT-1 antibody, kcnq1-A antibody, xkvlqt1 antibody, zgc:158384 antibody, AW559127 antibody, Kcna9 antibody, KvLQT1 antibody, potassium voltage-gated channel subfamily Q member 1 antibody, KCNQ potassium channel antibody, potassium voltage-gated channel, KQT-like subfamily, member 1 antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 antibody, voltage gated potassium channel subunit antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog antibody, potassium voltage-gated channel, subfamily Q, member 1 antibody, KCNQ1 antibody, KCNQ antibody, kcnq1 antibody, Kcnq1 antibody, kcnq1.L antibody
    Background
    Kv7.1 (KvLQT1) is a potassium channel protein coded for by the gene KCNQ1. Kv7.1 is present in the cell membranes of cardiac muscle tissue and in inner ear neurons (1) among other tissues. In the cardiac cells, Kv7.1 mediates the IKs (or slow delayed rectifying K+) current that contributes to the repolarization of the cell, terminating the cardiac action potential and thereby the heart's contraction (2, 3).
    Gene ID
    3784
    NCBI Accession
    NP_000209
    UniProt
    P51787
    Pathways
    Negative Regulation of Hormone Secretion, Sensory Perception of Sound
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