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RPS6KA1 antibody (C-Term) (Atto 390)

RPS6KA1 Reactivity: Human WB, ELISA, IP, IF, ICC Host: Rabbit Polyclonal Atto 390
Catalog No. ABIN2486884
  • Target See all RPS6KA1 Antibodies
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    Binding Specificity
    • 41
    • 30
    • 25
    • 18
    • 16
    • 16
    • 15
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 205
    • 123
    • 91
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 215
    • 17
    Rabbit
    Clonality
    • 192
    • 41
    Polyclonal
    Conjugate
    • 107
    • 17
    • 14
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    This RPS6KA1 antibody is conjugated to Atto 390
    Application
    • 184
    • 103
    • 54
    • 53
    • 50
    • 27
    • 24
    • 24
    • 14
    • 12
    • 9
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Detects ~90 kDa.
    Cross-Reactivity
    Cow, Human, Mouse, Rat
    Purification
    Peptide Affinity Purified
    Immunogen
    Human p90 RSK1 C-terminal peptide, conjugated to KLH
    Top Product
    Discover our top product RPS6KA1 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF (1:50)
    • optimal dilutions for assays should be determined by the user.
    Comment

    0.25 mg/ml was sufficient for detection of ABIN2486884 in lysates prepared from mouse brain, spleen and intestine.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.01 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))
    Alternative Name
    RSK1 (RPS6KA1 Products)
    Synonyms
    HU-1 antibody, MAPKAPK1A antibody, RSK antibody, RSK1 antibody, Rsk1 antibody, p90rsk antibody, rsk antibody, RPS6KA antibody, hu-1 antibody, mapkapk1a antibody, rsk1 antibody, wu:fc56h07 antibody, zgc:152654 antibody, ribosomal protein S6 kinase A1 antibody, ribosomal protein S6 kinase polypeptide 1 antibody, ribosomal protein S6 kinase A1-like antibody, ribosomal protein S6 kinase A1 L homeolog antibody, ribosomal protein S6 kinase a, polypeptide 1 antibody, RPS6KA1 antibody, Rps6ka1 antibody, RPS6KA1L antibody, rps6ka1.L antibody, rps6ka1 antibody
    Background
    The p90 ribosomal S6 kinase (Rsk) family comprises four mammalian serine/threonine kinases (Rsk1-4). In the past, S6K1 and S6K2 were thought to be the predominant operating S6 kinases, however RSK 1 and 2 have been shown to phosphorylate S6 in response to the ERK pathway, or otherwise known as the extra cellular signal-regulated kinases pathway. RSK 1 in particular is very multifunctional as it participates in nuclear signaling, regulates nuclear factors, regulates several transcription factors like c-Fos, and interacts with the transcriptional coactivator CREB-binding protein. As a result, RSK1 seems to have an important role in cellular growth control and proliferation. (1-5).
    Gene ID
    6195
    NCBI Accession
    NP_002944
    UniProt
    Q15418
    Pathways
    MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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