Cnpase antibody

Catalog No. ABIN2487360

Product Details anti-Cnpase Antibody

Target: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Reactivity: Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cnpase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Specificity: Specific for the ~ 46k CNP protein in Western blots

Cross-Reactivity: Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine)

Purification: Neat serum

Immunogen: Endogenous rabbit 2,3 cyclic nucleotide-3-phospho-diesterase

Application Details

Application Notes: Recommended Dilution: WB: 1:1000 IHC: 1:1000 (formalin-fixed, Ramaswamy et al. 1990) Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Neat serum

Storage: -20 °C

References for anti-Cnpase antibody (ABIN2487360)

González-Fernández, Jeong, Fukaya, Kim, Khawaja, Srivastava, Waisman, Son, Kang: "PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling." in: eLife, Vol. 7, (2019) (PubMed).

Target Details for Cnpase

Target: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Alternative Name: CNP (CNP Products)

Synonyms: CNP1 antibody, CNPase antibody, Cnp-1 antibody, Cnp1 antibody, CNPF antibody, CNPI antibody, CNPII antibody, CNP antibody, DKFZp469F1421 antibody, cnpl antibody, fd21d08 antibody, fi37a10 antibody, rich antibody, sb:cb662 antibody, si:ch73-158e11.4 antibody, wu:fd21d08 antibody, wu:fd44a05 antibody, wu:fi35d08 antibody, wu:fi37a10 antibody, cnp antibody, 2',3'-cyclic nucleotide 3' phosphodiesterase antibody, CNP antibody, Cnp antibody, cnp antibody, cnp.L antibody

Background: 2,3-cyclic nucleotide-3-phosphodiesterase (CNP) is a membrane bound, microtubule associated protein that is among the most abundant myelin proteins of the CNS. It is thought that CNP may serve as a regulator of tubulin polymerization and of microtubule distribution (Bifulco et al., 2002). It was recently found that CNP may also function as a possible linker protein anchoring microtubules to the plasma membrane via a 13 residue C-terminal CNP fragment (Bifulco et al., 2002, Esposito et al., 2008). Anti-CNP Western blot of rat brain lysate showing the specific immunolabeling of the ~ 46k CNP protein.

Molecular Weight: '46 kDa

Gene ID: 25275

UniProt: P13233