TNFSF11 antibody (Tumor Necrosis Factor (Ligand) Superfamily, Member 11) (AA 1-317)

Details for Product anti-TNFSF11 Antibody No. ABIN252546, Supplier: Log in to see
Antigen
  • CD254
  • ODF
  • OPGL
  • OPTB2
  • RANKL
  • TRANCE
  • hRANKL2
  • sOdf
  • TNFSF11
  • Ly109l
  • OPG
  • Trance
  • cd254
  • odf
  • opgl
  • optb2
  • rankl
  • sodf
  • tnfsf11
  • trance
  • TNF superfamily member 11
  • TNF receptor superfamily member 11b
  • tumor necrosis factor (ligand) superfamily, member 11
  • TNF superfamily member 11 L homeolog
  • TNFSF11
  • TNFRSF11B
  • Tnfsf11
  • tnfsf11.L
Alternatives
anti-Human TNFSF11 antibody for Enzyme Immunoassay
Epitope
AA 1-317
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Mouse
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Clonality (Clone)
Monoclonal ()
Conjugate
This TNFSF11 antibody is un-conjugated
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Application
Chromatin Immunoprecipitation (ChIP), Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Options
Supplier
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Supplier Product No.
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Immunogen A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse TRANCE was used as immunogen (NP_003692).
Clone 12A668
Isotype IgG1 kappa
Purification Protein G purified
Sterility Sterile filtered
Plasmids, Primers & others Plasmids, Primers & others TNFSF11 products on genomics-online (e.g. as negative or positive controls)
Alternative Name CD254 / RANKL (TNFSF11 Antibody Abstract)
Background Gene Symbol: TNFSF11
Molecular Weight Theoretical MW: 35 kDa
Gene ID 8600
NCBI Accession NP_003692
Pathways NF-kappaB Signaling
Application Notes Western Blot 1-2 μg/mL, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin 1 - 5 μg/mL, Chromatin Immunoprecipitation (ChIP), CyTOF-readyStaining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.Use in chromatin immunoprecipitation reported in scientific literature (PMID 25859979) The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Sterile - filtered PBS
Buffer contains: No Preservative
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 1-317) antibody (ABIN252546) Western blot analysis of TRANCE/RANKL in transfected cells. A single protein band of ...
Western Blotting (WB) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 1-317) antibody (ABIN252546) Western Blot: TRANCE/TNFSF11/RANK L Antibody (12A668) - Azide Free [ABIN2525463] - An...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 1-317) antibody (ABIN252546) Immunohistochemistry-Paraffin: TRANCE/TNFSF11/RANK L Antibody (12A668) - Azide Free [...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 11 (TNFSF11) (AA 1-317) antibody (ABIN252546) Immunohistochemistry-Paraffin: TRANCE/TNFSF11/RANK L Antibody (12A668) - Azide Free [...
Product cited in: Shin, Matsuo, Tada, Fukushima, Furuta, Ozeki, Kadowaki, Yamamoto, Okamoto, Jimi: "The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone invasion by oral squamous cell carcinoma cells." in: Carcinogenesis, Vol. 32, Issue 11, pp. 1634-40, 2011 (PubMed).

Hu, Chu, Zhu, Yang, Luthringer, Prins, Habib, Wang, Wang, Chung, Zhau: "Multiplexed quantum dot labeling of activated c-Met signaling in castration-resistant human prostate cancer." in: PLoS ONE, Vol. 6, Issue 12, pp. e28670, 2011 (PubMed).

Ghoreishi, Bach, Obst, Komba, Fleet, Dutz: "Expansion of antigen-specific regulatory T cells with the topical vitamin d analog calcipotriol." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 10, pp. 6071-8, 2009 (PubMed).

Parrula, Zimmerman, Nadella, Shu, Rosol, Fernandez, Lairmore, Niewiesk: "Expression of tumor invasion factors determines systemic engraftment and induction of humoral hypercalcemia in a mouse model of adult T-cell leukemia." in: Veterinary pathology, Vol. 46, Issue 5, pp. 1003-14, 2009 (PubMed).

Sandra, Hendarmin, Kukita, Nakao, Nakamura, Nakamura: "Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone." in: Oral oncology, Vol. 41, Issue 6, pp. 637-44, 2005 (PubMed).

Rubin, Chung, Fan, Zhu, Murphy, Nanes, Rosen: "Prostate carcinoma cells that have resided in bone have an upregulated IGF-I axis." in: The Prostate, Vol. 58, Issue 1, pp. 41-9, 2003 (PubMed).

Kikuchi, Matsuguchi, Tsuboi, Mitani, Tanaka, Matsuoka, Yamamoto, Hishikawa, Noguchi, Yoshikai: "Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 5, pp. 3574-9, 2001 (PubMed).

Pearse, Sordillo, Yaccoby, Wong, Liau, Colman, Michaeli, Epstein, Choi: "Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11581-6, 2001 (PubMed).

Fiumara, Snell, Li, Mukhopadhyay, Younes, Gillenwater, Cabanillas, Aggarwal, Younes: "Functional expression of receptor activator of nuclear factor kappaB in Hodgkin disease cell lines." in: Blood, Vol. 98, Issue 9, pp. 2784-90, 2001 (PubMed).

Hsu, Lacey, Dunstan, Solovyev, Colombero, Timms, Tan, Elliott, Kelley, Sarosi, Wang, Xia, Elliott, Chiu, Black, Scully, Capparelli, Morony, Shimamoto, Bass, Boyle: "Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 7, pp. 3540-5, 1999 (PubMed).

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