EIF3G antibody (AA 51-150)

Catalog No. ABIN2559611

Product Details anti-EIF3G Antibody

Target: EIF3G (Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF3G antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EIF3S4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EIF3G

Target: EIF3G (Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G))

Alternative Name: EIF3S4 (EIF3G Products)

Synonyms: EIF3-P42 antibody, EIF3S4 antibody, eIF3-delta antibody, eIF3-p44 antibody, 44kDa antibody, D0Jmb4 antibody, Eif3s4 antibody, TU-189B2 antibody, p44 antibody, eif3s4 antibody, zgc:56553 antibody, eIF3g-A antibody, eif3s4-A antibody, eIF3g antibody, eIF3-S4 antibody, An16g05260 antibody, AO090011000648 antibody, eukaryotic translation initiation factor 3 subunit G antibody, eukaryotic translation initiation factor 3, subunit G antibody, eukaryotic translation initiation factor 3 subunit G S homeolog antibody, Eukaryotic translation initiation factor 3 subunit G antibody, eukaryotic translation initiation factor antibody, EIF3G antibody, Eif3g antibody, eif3g antibody, eif3g.S antibody, eif-3.G antibody, eIF3g antibody, ANI_1_732144 antibody, AOR_1_1112054 antibody, VDBG_00824 antibody, MGYG_08099 antibody, Tsp_04379 antibody

Background:

Synonyms: EIF3S4, EIF3-P42, eIF3-p44, eIF3-delta, Eukaryotic translation initiation factor 3 subunit G, eIF3g, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, Eukaryotic translation initiation factor 3 subunit 4, eIF-3-delta, eIF3 p42, eIF3 p44

Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.

Gene ID: 8666

UniProt: O75821

Pathways: Ribonucleoprotein Complex Subunit Organization