HSPH1 antibody (Isoform alpha, N-Term)

Catalog No. ABIN263997

Product Details anti-HSPH1 Antibody

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Binding Specificity: AA 1-858, Isoform alpha, N-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSPH1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Heat Shock Protein 105 alpha (HSP105a).

Characteristics: Synonyms: Heat shock 110 kDa protein, Antigen NY-CO-25, HSPH1, HSP-105, HSP110, KIAA0201

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human HSP105 α (1-858 aa) purified from E. coli

Clone: J1G12

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot: 1: 500 approx. 1,000 (starting dilution 1: 1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for HSPH1

Target: HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))

Alternative Name: Heat Shock Protein 105 / HSP105 (HSPH1 Products)

Background: Hsp105 is a mammalian member of the HSP105/110 family, a diverged subgroup of the HSP70 family. HSP105 exists as two isoforms, alpha and beta. Hsp105 alpha associates with Hsp70/Hsc70 as complexes in vivo and regulates the chaperone activity of Hsp70/Hsc70 negatively in vitro and in vivo. Hsp105 α is constitutively expressed and also induced by various stress, whereas Hsp105 β, lacking 44 amino acids from Hsp105 α, is specifically expressed during mild heat shock. Although Hsp105 α is shown to localize in the cytoplasm of mammalian cells, cellular localization of Hsp105 β is not known.Synonyms: Antigen NY-CO-25, HSP-105, HSP110, HSPH1, Heat shock 110 kDa protein, KIAA0201

Gene ID: 10808

UniProt: Q92598