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CYP3A5 antibody (C-Term)

CYP3A5 Reactivity: Human WB, EIA, IHC (fro) Host: Mouse Monoclonal F18 P3 B6 unconjugated
Catalog No. ABIN264500
  • Target See all CYP3A5 Antibodies
    CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
    Binding Specificity
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 23
    • 12
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 21
    • 2
    Mouse
    Clonality
    • 22
    • 1
    Monoclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP3A5 antibody is un-conjugated
    Application
    • 16
    • 8
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody reacts to Cytochrome P450 3A5.
    Characteristics
    Synonyms: Cytochrome P450 3A5, Cytochrome P450-PCN3, Cytochrome P450 HLp2
    Purification
    Purified
    Immunogen
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the Cterminus of the human CYP3A5 protein and mousemyeloma Ag8563 cells.
    Clone
    F18 P3 B6
    Isotype
    IgG1
    Top Product
    Discover our top product CYP3A5 Primary Antibody
  • Application Notes
    ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL. When used in conjunction with CYP3A7 (Cat. No. ABIN264501), can differentiate betweenthe CYP3A family members, 3A5 and 3A7. Positive Control: Squamous oesophagus cancer.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline with 0.08 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
    Alternative Name
    CYP3A5 (CYP3A5 Products)
    Synonyms
    CP35 antibody, CYPIIIA5 antibody, P450PCN3 antibody, PCN3 antibody, cytochrome P450 family 3 subfamily A member 5 antibody, CYP3A5 antibody
    Background
    CYP3A genes encode monooxygenases, enzymes which catalyze drug metabolism and the synthesis of cholesterol, steroids and other lipids. CYP3A (cytochrome P450, family 3, subfamily A), the most abundant p450 enzyme in human liver, is responsible for the metabolism of more than 50 % of all clinical drugs. CYP3A members localize in organs that associate with drug disposition, including the liver, gastrointestinal tract and kidney. The CYP3A cluster consists of four genes: CYP3A43, CYP3A4, CYP3A7 and CYP3A5, and two pseudogenes: CYP3A5P1 and CYP3A5P2. The CYP3A cluster maps to gene locus 7q21.3-q22.1.Synonyms: Cytochrome P450 3A5, Cytochrome P450 HLp2, Cytochrome P450-PCN3
    Gene ID
    1577
    UniProt
    P20815
    Pathways
    Steroid Hormone Biosynthesis
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