Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

IRF7 antibody (Middle Region)

IRF7 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN265130
  • Target See all IRF7 Antibodies
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    Binding Specificity
    • 17
    • 17
    • 15
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 70
    • 55
    • 54
    • 17
    • 8
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 69
    • 2
    Rabbit
    Clonality
    • 58
    • 13
    Polyclonal
    Conjugate
    • 24
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IRF7 antibody is un-conjugated
    Application
    • 50
    • 18
    • 15
    • 14
    • 14
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Specificity
    This antibody reacts to Interferon regulatory factor 7 (IRF7).
    Purification
    Purified
    Immunogen
    Rabbit polyclonal IRF7 antibody was raised against a peptide corresponding to 14 amino acids near the center of human IRF7
    Isotype
    IgG
    Top Product
    Discover our top product IRF7 Primary Antibody
  • Application Notes
    Western Blot: 1 - 2 μg/mL. Expressed predominantly in spleen, thymus and peripheral blood leukocytes, IRF7 islocated in the nucleus and cytoplasm. The phosphorylated and active form accumulatesselectivly in the nucleus.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate buffered saline with 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Target
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    Alternative Name
    IRF7 (IRF7 Products)
    Synonyms
    wu:fl24c03 antibody, zgc:66043 antibody, zgc:77947 antibody, IRF7 antibody, irf7 antibody, IRF-7H antibody, IRF7A antibody, IRF7B antibody, IRF7C antibody, IRF7H antibody, interferon regulatory factor 7 antibody, irf7 antibody, IRF7 antibody, Irf7 antibody
    Background
    Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling (3,4). There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.Synonyms: IRF-7, Interferon regulatory factor 7
    Gene ID
    3665
    NCBI Accession
    NP_001563
    UniProt
    Q92985
    Pathways
    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
You are here:
Support