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TFAP2A antibody
TFAP2A
Reactivity: Human, Mouse, Rat
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TFAP2A Antibody
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Target
See all TFAP2A Antibodies
TFAP2A
(Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
Reactivity
All reactivities for TFAP2A antibodies
Human, Mouse, Rat
Host
All hosts for TFAP2A antibodies
Rabbit
Clonality
All clonalities for TFAP2A antibodies
Polyclonal
Conjugate
All conjugates for TFAP2A antibodies
This TFAP2A antibody is un-conjugated
Application
All applications for TFAP2A antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody detects endogenous levels of TFAP2A / AP-2 alpha protein (region surrounding Lys431).
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen
Purity
> 95 % pure by SDS-PAGE
Top Product
Discover our top product TFAP2A Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for TFAP2A
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Target
TFAP2A
(Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
Alternative Name
TFAP2A / AP-2 alpha (TFAP2A Products )
Synonyms
TFAP2A antibody, Ap-2 antibody, AP-2 antibody, AP-2alpha antibody, AP2TF antibody, BOFS antibody, TFAP2 antibody, ap2 antibody, xap2 antibody, XAP-2 antibody, ap2tf antibody, tfap2 antibody, ap-2alpha antibody, tfap2alpha antibody, cb93 antibody, fb83f04 antibody, fc31a07 antibody, wu:fb83f04 antibody, wu:fc31a07 antibody, tfap2a-a antibody, tcfap2a antibody, ap2a antibody, AP2alpha antibody, Ap2 antibody, Ap2tf antibody, Tcfap2a antibody, AP2 antibody, transcription factor AP-2 alpha antibody, transcription factor AP-2 antibody, tto transcription factor AP-2 alpha antibody, to transcription factor AP-2 alpha L homeolog antibody, to transcription factor AP-2 alpha S homeolog antibody, Transcription factor AP-2 alpha antibody, transcription factor AP-2, alpha antibody, TFAP2A antibody, LOC100302602 antibody, tfap2a antibody, tfap2a.L antibody, tfap2a.S antibody, ap2a antibody, Tfap2a antibody
Background
The AP2 proteins are normally expressed in ectodermally derived vertebrate tissues where they are necessary for normal growth and development. The factors have also been implicated in the control of cell proliferation, viral transformation, and oncogenesis. AP2 seems to play in important role in human breast cancer.AP2 alpha is the only AP2 protein required for early morphogenesis of the lens vesicle. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.Synonyms: AP-2 transcription factor, AP2, AP2TF, Activating enhancer-binding protein 2-alpha, Activator protein 2, TFAP2
Molecular Weight
approx. 50 kDa
Gene ID
7020
NCBI Accession
NP_001027451
UniProt
P05549
Pathways
Caspase Cascade in Apoptosis , EGFR Signaling Pathway , Response to Water Deprivation , Sensory Perception of Sound , Tube Formation , Embryonic Body Morphogenesis , Brown Fat Cell Differentiation , Lipid Metabolism
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