SLC2A3 antibody

Catalog No. ABIN265443

Product Details anti-SLC2A3 Antibody

Target: SLC2A3 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC2A3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects endogenous levels of GLUT3 protein. (region surrounding Glu482)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1: 1000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SLC2A3

Target: SLC2A3 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 3 (SLC2A3))

Alternative Name: GLUT3 / SLC2A3 (SLC2A3 Products)

Synonyms: slc2a3 antibody, wu:fb92c06 antibody, zgc:92476 antibody, SLC2A3 antibody, GLUT3 antibody, AA408729 antibody, AL023014 antibody, AL024341 antibody, AU040424 antibody, C78366 antibody, Glut-3 antibody, Glut3 antibody, CEF-GT3 antibody, GLUT-3 antibody, SLC2A14 antibody, solute carrier family 2 (facilitated glucose transporter), member 3a antibody, solute carrier family 2 member 3 antibody, solute carrier family 2 (facilitated glucose transporter), member 3 antibody, solute carrier family 2 member 14 antibody, solute carrier family 2, facilitated glucose transporter member 3 antibody, slc2a3a antibody, SLC2A3 antibody, Slc2a3 antibody, SLC2A14 antibody, LOC100125981 antibody

Background: Glucose is the major source of our energy and there are numerous isoforms of the glucose transporter in mammals, including Glut1, Glut2, Glut3, Glut4, Glut5, Glut6, Glut7, Glut8 and Glut9. The Glut5 gene located on the short arm of human chromosome 1 encodes a 501-amino acid facilitative glucose transporter. Glut5 mRNA is highly expressed in small intestine and to a lesser extent in kidney, skeletal muscle and adipose tissue. Glut5 plays a critical role in fructose absorption in the small intestine and its expression is highly induced when exposed to a fructose-enriched diet. Glut5 transporter expressed in human skeletal muscle is specifically localized to the plasma membrane, where it participates in regulating hexose transfer across the sarcolemma. Glut8, a novel glucose transporter-like protein, exhibits significant sequence similarity with the other members of sugar transporter family. Glut8 comprises 12 putative membrane-spanning helices and several conserved motifs, which are important for transport activity. In human tissues, Glut8 is predominantly expressed in testis and, to a lesser extent, in most other tissues including skeletal muscle, heart, small intestine and brain.Synonyms: GLUT-3, Glucose transporter 3, Glucose transporter type 3 brain, Solute carrier family 2 facilitated glucose transporter member 3

Molecular Weight: approx. 54.0 kDa

Gene ID: 6515

NCBI Accession: NP_008862

UniProt: P11169

Pathways: Warburg Effect