MMP19 antibody

Catalog No. ABIN265528

Product Details anti-MMP19 Antibody

Target: MMP19 (Matrix Metallopeptidase 19 (MMP19))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of MMP-19 protein. (region surrounding Gly44)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Affinity Chromatography using epitope-specific immunogen

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MMP19

Target: MMP19 (Matrix Metallopeptidase 19 (MMP19))

Alternative Name: MMP-19 (MMP19 Products)

Synonyms: mmp18 antibody, mmp-18 antibody, mmp-19 antibody, col4 antibody, MMP18 antibody, RASI-1 antibody, matrix metallopeptidase 19 antibody, matrix metallopeptidase 1 S homeolog antibody, mmp19 antibody, mmp1.S antibody, MMP19 antibody, Mmp19 antibody

Background: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.Synonyms: MMP-18, MMP18, MMP19, Matrix metalloproteinase RASI, Matrix metalloproteinase-19, RASI

Molecular Weight: approx. 57 kDa

Gene ID: 4327

NCBI Accession: NP_002420

UniProt: Q99542