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IL3RA antibody

IL3RA Reactivity: Human MA Host: Mouse Monoclonal 6H6 unconjugated
Catalog No. ABIN2664180
  • Target See all IL3RA Antibodies
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Reactivity
    • 81
    • 26
    • 3
    Human
    Host
    • 48
    • 36
    • 3
    • 1
    Mouse
    Clonality
    • 45
    • 42
    • 1
    Monoclonal
    Conjugate
    • 45
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL3RA antibody is un-conjugated
    Application
    • 60
    • 50
    • 19
    • 15
    • 13
    • 13
    • 10
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Multiplex Assay (MA)
    Cross-Reactivity
    Rhesus Monkey
    Purification
    The antibody was purified by affinity chromatography.
    Clone
    6H6
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product IL3RA Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IL3RA (Interleukin 3 Receptor, alpha (IL3RA))
    Alternative Name
    CD123 (IL3RA Products)
    Synonyms
    CD123 antibody, IL3R antibody, IL3RAY antibody, IL3RX antibody, IL3RY antibody, hIL-3Ra antibody, CDw123 antibody, SUT-1 antibody, Cyrl antibody, interleukin 3 receptor subunit alpha antibody, interleukin 3 receptor, alpha chain antibody, IL3RA antibody, Il3ra antibody
    Background
    CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity, when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.
    Pathways
    JAK-STAT Signaling
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