HDAC2 antibody (AA 473-488)

Catalog No. ABIN2668730

Product Details anti-HDAC2 Antibody

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Binding Specificity: AA 473-488

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This HDAC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Cleavage Under Targets and Release Using Nuclease (CUT&RUN)

Purification: Culture Supernatant

Immunogen: This HDAC2 antibody was raised against a KLH-conjugated peptide corresponding to amino acids 473-488 of human HDAC2.

Clone: 3F3

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-HDAC2 antibody (ABIN2668730)

Cohen, Idan, Rider, Peleg, Vornov, Elena, Tomas, Martin, Tudor, Cicerone, Wegner, Mareike, Brondani, Lydia, Freudenberg, Marina, Mittler, Gerhard, Ferrando-May, Elisa, Dinarello, Apte, Ron, Schneider et al.: "IL-1α is a DNA damage sensor linking genotoxic stress signaling to sterile inflammation and innate immunity. ..." in: Scientific reports, Vol. 5, pp. 14756, (2015) (PubMed).

Qiang, Denny, Lieu, Carreon, Li: "Histone H3K9 modifications are a local chromatin event involved in ethanol-induced neuroadaptation of the NR2B gene." in: Epigenetics, Vol. 6, Issue 9, pp. 1095-104, (2012) (PubMed).

Nayak, Glöckner-Pagel, Vaeth, Schumann, Buttmann, Bopp, Schmitt, Serfling, Berberich-Siebelt: "Sumoylation of the transcription factor NFATc1 leads to its subnuclear relocalization and interleukin-2 repression by histone deacetylase." in: The Journal of biological chemistry, Vol. 284, Issue 16, pp. 10935-46, (2009) (PubMed).

Target Details for HDAC2

Target: HDAC2 (Histone Deacetylase 2 (HDAC2))

Alternative Name: HDAC2 (HDAC2 Products)

Synonyms: HD2 antibody, RPD3 antibody, YAF1 antibody, D10Wsu179e antibody, Yy1bp antibody, mRPD3 antibody, HISTONE DEACETYLASE antibody, T1N24.9 antibody, T1N24_9 antibody, histone deacetylase 2 antibody, histone deacetylase 2 antibody, histone deacetylase 2 S homeolog antibody, HDAC2 antibody, Hdac2 antibody, hdac2.S antibody, HDA2 antibody

Molecular Weight: 55 kDa

Gene ID: 3066

Pathways: Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection