NR1H2 antibody (N-Term)

Catalog No. ABIN2668732

The Rabbit Polyclonal anti-NR1H2 antibody has been validated for WB, ChIP-seq and ChIP. It is suitable to detect NR1H2 in samples from Human. There are 2+ publications available.

Quick Overview for NR1H2 antibody (N-Term) (ABIN2668732)

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR1H2 antibody is un-conjugated

Application: Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP)

Product Details anti-NR1H2 Antibody

Binding Specificity: N-Term

Purification: Affinity Purified

Immunogen: This LXR-beta antibody was raised against a peptide in the N-terminal region of human LXR-beta.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-NR1H2 antibody (ABIN2668732)

Savic, Ramaker, Roberts, Dean, Burwell, Meadows, Cooper, Garabedian, Gertz, Myers: "Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation." in: Genome medicine, Vol. 8, Issue 1, pp. 74, (2016) (PubMed).

Pencheva, Buss, Posada, Merghoub, Tavazoie: "Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation." in: Cell, Vol. 156, Issue 5, pp. 986-1001, (2014) (PubMed).

Target Details for NR1H2

Target: NR1H2 (Nuclear Receptor Subfamily 1, Group H, Member 2 (NR1H2))

Alternative Name: LXR-beta

Molecular Weight: 55 kDa

Gene ID: 7376

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding