SREBF2 antibody (AA 833-1141)

Catalog No. ABIN2668815

Product Details anti-SREBF2 Antibody

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Binding Specificity: AA 833-1141

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SREBF2 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Purification: Protein G Chromatography

Immunogen: This SREBP-2 antibody was raised against a recombinant protein corresponding to amino acids 833-1141 of human SREBP-2.

Clone: IgG-1C6

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-SREBF2 antibody (ABIN2668815)

Ratovitski: "Delta Np63 alpha – Responsive microRNA Modulate the Expression of Metabolic Enzymes." in: Current pharmaceutical biotechnology, Vol. 16, Issue 9, pp. 832-50, (2015) (PubMed).

Daniëls, Smans, Royaux, Chypre, Swinnen, Zaidi: "Cancer cells differentially activate and thrive on de novo lipid synthesis pathways in a low-lipid environment." in: PLoS ONE, Vol. 9, Issue 9, pp. e106913, (2014) (PubMed).

Target Details for SREBF2

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Alternative Name: SREBP-2 (SREBF2 Products)

Synonyms: SREBF2 antibody, srebp2 antibody, SREBP2 antibody, zgc:158371 antibody, AI608257 antibody, SREBP-2 antibody, SREBP2gc antibody, bHLHd2 antibody, lop13 antibody, nuc antibody, Srebf2_retired antibody, sterol regulatory element binding transcription factor 2 antibody, sterol regulatory element binding factor 2 antibody, sterol regulatory element binding transcription factor 2 L homeolog antibody, SREBF2 antibody, srebf2 antibody, Srebf2 antibody, srebf2.L antibody

Molecular Weight: 68 and 125 kDa

Gene ID: 6721

Pathways: Regulation of Lipid Metabolism by PPARalpha