Immunoglobulin kappa Variable 1-27 (IGKV1-27) antibody

Catalog No. ABIN2668824

Product Details

Target:

Immunoglobulin kappa Variable 1-27 (IGKV1-27)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Western Blotting (WB)

Purification: Affinity Purified

Immunogen: This A20 antibody was raised against a full-length protein corresponding to human A20.

Clone: 59A426

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -80 °C

Storage Comment: Antibodies in solution can be stored at -80 °C for 2 years.

Expiry Date: 6 months

References

Wu, Xu, Chang: "The promyelocytic leukemia protein represses A20-mediated transcription." in: The Journal of biological chemistry, Vol. 277, Issue 35, pp. 31734-9, 2002 (PubMed).

Target Details

Target:

Immunoglobulin kappa Variable 1-27 (IGKV1-27)

Alternative Name: A20 (IGKV1-27 Antibody Abstract)

Synonyms: A20, OTUD7C, TNFA1P2, TNF alpha induced protein 3, TNFAIP3

Background: A20 is a zinc finger protein induced by Tumor Necrosis Factor (TNF) and involved in limiting inflammation through inhibition of NFκB (NFκB p50 and NFκB p65) activation. A20 also inhibits TNF-mediated apoptosis. A20 is also known as TNFA1P2, TNFAIP3 and OTUD7C.

Molecular Weight: 70 kDa

Gene ID: 7128

Pathways: Activation of Innate immune Response