CD103 antibody

Catalog No. ABIN2688873

Product Details anti-CD103 Antibody

Target: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD103 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Brand: BD Pharmingen™

Characteristics: Reacts with the human mucosal lymphocyte antigen 1 (HML-1), a type I transmembrane molecule, 175 kDa, also known as integrin αE. It is found on >90 % of intestinal intraepithelial lymphocytes (iIEL) associated with integrin β7. CD103 is also expressed on lamina propria T lymphocytes in the intestine and on PHA-stimulated peripheral blood lymphocytes. It is rarely expressed on resting peripheral blood lymphocytes. It has been suggested that CD103 may have an accessory function for activation of iIEL. CD103 has been reported as a useful tool in hairy cell leukemia research. Profile of PHA-stimulated (3 days) peripheral blood mononuclear cells (PBMC) analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD103 - Purified - Clone Ber-ACT8 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: Ber

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD103 antibody (ABIN2688873)

DiGiuseppe, Borowitz: "Clinical utility of flow cytometry in the chronic lymphoid leukemias." in: Seminars in oncology, Vol. 25, Issue 1, pp. 6-10, (1998) (PubMed).

Matutes, Meeus, McLennan, Catovsky: "The significance of minimal residual disease in hairy cell leukaemia treated with deoxycoformycin: a long-term follow-up study." in: British journal of haematology, Vol. 98, Issue 2, pp. 375-83, (1997) (PubMed).

Target Details for CD103

Target: CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))

Alternative Name: CD103 (ITGAE Products)

Synonyms: A530055J10 antibody, CD103 antibody, aM290 antibody, alpha-E1 antibody, alpha-M290 antibody, HUMINAE antibody, integrin alpha E, epithelial-associated antibody, integrin subunit alpha E antibody, Itgae antibody, ITGAE antibody