CD109 antibody

Catalog No. ABIN2688889

Product Details anti-CD109 Antibody

Target: CD109

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD109 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Brand: BD Pharmingen™

Characteristics: Reacts with a 150-170 kDa glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed on activated T cells, myeloid progenitor (CD34+) and mature myeloid lineage cells (monocytes, granulocytes, platelets), but not on CD34+ lymphoid progenitor cells. CD109 is also expressed on vein and artery endothelial cells. The expression of CD109 is upregulated on PHA-stimulated T cells. CD109 has been reported to be present on long-term adult bone marrow cultured cells, where it is co-expressed with CD34 and CD90. Its biological role in hematopoiesis has not been fully elucidated. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood monocytes analyzed on a FACScan Profile of peripheral blood granulocytes analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD109 - Purified - Clone TEA 2/16 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: TEA 2-16

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD109 antibody (ABIN2688889)

Smith, Hayward, Horsewood, Warkentin, Denomme, Kelton: "Characterization and localization of the Gova/b alloantigens to the glycosylphosphatidylinositol-anchored protein CDw109 on human platelets." in: Blood, Vol. 86, Issue 7, pp. 2807-14, (1995) (PubMed).

Target Details for CD109

Target: CD109

Alternative Name: CD109 (CD109 Products)

Synonyms: CPAMD7 antibody, RP11-525G3.1 antibody, CD109 antibody, 9930012E15Rik antibody, AI480638 antibody, GARP antibody, CD109 molecule antibody, CD109 antigen antibody, CD109 antibody, Cd109 antibody, cd109 antibody

Pathways: Activated T Cell Proliferation