IL2RG antibody

Catalog No. ABIN2688953

Product Details anti-IL2RG Antibody

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivity: Human, Dog

Host: Rat

Clonality: Monoclonal

Conjugate: This IL2RG antibody is un-conjugated

Application: Flow Cytometry (FACS)

Brand: BD Pharmingen™

Characteristics: This antibody reacts with the 65-70 kDa common γ subunit (γc) shared by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptors. The γc receptor is a glycoprotein expressed by most peripheral T and B lymphocytes, NK cells, monocytes, and granulocytes. The cytoplasmic domain of the γc chain plays an important role in cytokine-mediated signal transduction. By immunofluorescent staining and flow cytometric analysis, the TUGh4 antibody has been shown to specifically recognize human γc expressed by cell lines, including human γc gene-transfected cell lines, which are known to express the human γc chain.

BD Pharmingen™ Purified Rat Anti-Human CD132 - Purified - Clone TUGh4 - Isotype Rat IgG2b, κ - Reactivity Hu, Dog - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: TUGh4

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-IL2RG antibody (ABIN2688953)

Ishii, Takeshita, Kimura, Tada, Kondo, Nakamura, Sugamura: "Expression of the IL-2 receptor gamma chain on various populations in human peripheral blood." in: International immunology, Vol. 6, Issue 8, pp. 1273-7, (1995) (PubMed).

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: CD132 (IL2RG Products)

Synonyms: Ab2-183 antibody, Cd132 antibody, CD132 antibody, CIDX antibody, IL-2RG antibody, IMD4 antibody, P64 antibody, SCIDX antibody, SCIDX1 antibody, [g]c antibody, gamma(c) antibody, gc antibody, interleukin 2 receptor subunit gamma antibody, interleukin 2 receptor subunit gamma L homeolog antibody, interleukin 2 receptor, gamma chain antibody, IL2RG antibody, il2rg.L antibody, Il2rg antibody

Background: Synonyms: common γ chain

Pathways: JAK-STAT Signaling, Growth Factor Binding