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LY75/DEC-205 antibody

LY75 Reactivity: Human FACS Host: Mouse Monoclonal MMRI unconjugated
Catalog No. ABIN2689081
  • Target See all LY75/DEC-205 (LY75) Antibodies
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    Reactivity
    • 42
    • 30
    • 6
    • 5
    • 2
    • 2
    Human
    Host
    • 40
    • 18
    • 6
    • 1
    • 1
    Mouse
    Clonality
    • 33
    • 32
    • 1
    Monoclonal
    Conjugate
    • 28
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This LY75/DEC-205 antibody is un-conjugated
    Application
    • 23
    • 22
    • 20
    • 18
    • 14
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Flow Cytometry (FACS)
    Brand
    BD Pharmingen™
    Characteristics
    Reacts with DEC-205, a 205 kDa transmembrane protein with C-type lectin external domains, present on dendritic cells (DC) and some epithelia. It is being described as a multilectin receptor for adsorptive endocytosis. Reports indicate that CD205 (DEC-205) mRNA levels increase significantly during activation. In monocyte derived dendritic cells, the expression of CD205 increased during maturation. Antibody MMRI-7 is useful for the study of DC development. Profile of CD205 (MMRI-7) reactivity on peripheral blood monocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

    BD Pharmingen™ Purified Mouse Anti-Human CD205 - Purified - Clone MMRI-7 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    MMRI
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product LY75 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C.
  • Kato, Neil, Fearnley, McLellan, Vuckovic, Hart: "Expression of multilectin receptors and comparative FITC-dextran uptake by human dendritic cells." in: International immunology, Vol. 12, Issue 11, pp. 1511-9, (2000) (PubMed).

    Guo, Gong, Maric, Misulovin, Pack, Mahnke, Nussenzweig, Steinman: "A monoclonal antibody to the DEC-205 endocytosis receptor on human dendritic cells." in: Human immunology, Vol. 61, Issue 8, pp. 729-38, (2000) (PubMed).

    Kato, Neil, Clark, Morris, Sorg, Hart: "cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells." in: Immunogenetics, Vol. 47, Issue 6, pp. 442-50, (1998) (PubMed).

  • Target
    LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))
    Alternative Name
    CD205 (LY75 Products)
    Synonyms
    LY75 antibody, MGC140308 antibody, DEC205 antibody, im:7150926 antibody, si:dkey-78p20.2 antibody, LYT75 antibody, CD205 antibody, DEC-205 antibody, CLEC13B antibody, GP200-MR6 antibody, LY-75 antibody, RGD1565962 antibody, Ly-75 antibody, lymphocyte antigen 75 antibody, CD205 protein antibody, CD302 antigen antibody, LY75 antibody, Cyan7822_2917 antibody, LY5 antibody, ly75 antibody, cd205 antibody, LOC100380704 antibody, LOC100433861 antibody, LOC100483541 antibody, Ly75 antibody
    Background
    Synonyms: DEC-205
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