CD57 antibody

Catalog No. ABIN2689343

Product Details anti-CD57 Antibody

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD57 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Brand: BD Pharmingen™

Characteristics: Reacts with a 110 kDa carbohydrate antigen associated with myelin-associated glycoprotein expressed on 7-35 % of normal peripheral blood lymphocytes including a subset of natural killer cells, a subset of CD8+ peripheral blood suppressor/cytotoxic T cells, and on some neural tissues. CD57 is not expressed on granulocytes, platelets, red blood cells or thymocytes. The function of CD57 is still unclear, however, its expression on T-cell subets occurs in late immune responses. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood lymphocytes analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD57 - Purified - Clone NK-1 - Isotype Mouse IgM, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: NK

Isotype: IgM kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD57 antibody (ABIN2689343)

dAngeac, Monier, Pilling, Travaglio-Encinoza, Rème, Salmon: "CD57+ T lymphocytes are derived from CD57- precursors by differentiation occurring in late immune responses." in: European journal of immunology, Vol. 24, Issue 7, pp. 1503-11, (1994) (PubMed).

McGarry, Helfand, Quarles, Roder: "Recognition of myelin-associated glycoprotein by the monoclonal antibody HNK-1." in: Nature, Vol. 306, Issue 5941, pp. 376-8, (1984) (PubMed).

Abo, Cooper, Balch: "Characterization of HNK-1+ (Leu-7) human lymphocytes. I. Two distinct phenotypes of human NK cells with different cytotoxic capability." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 129, Issue 4, pp. 1752-7, (1982) (PubMed).

Target Details for CD57

Target: CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))

Alternative Name: CD57 (B3GAT1 Products)

Synonyms: CD57 antibody, GLCATP antibody, GLCUATP antibody, HNK1 antibody, LEU7 antibody, NK-1 antibody, NK1 antibody, 0710007K08Rik antibody, AI846286 antibody, GlcAT-P antibody, Glcatp antibody, Hnk1 antibody, Hnk-1 antibody, b3gat1 antibody, si:dkey-22o20.1 antibody, cd57 antibody, glcatp antibody, glcuatp antibody, hnk-1 antibody, hnk1 antibody, leu7 antibody, nk-1 antibody, nk1 antibody, beta-1,3-glucuronyltransferase 1 antibody, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) antibody, beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a antibody, beta-1,3-glucuronyltransferase 1 L homeolog antibody, B3GAT1 antibody, B3gat1 antibody, b3gat1a antibody, b3gat1.L antibody

Pathways: Glycosaminoglycan Metabolic Process