CD83 antibody

Catalog No. ABIN2689416

Product Details anti-CD83 Antibody

Target: CD83

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD83 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Brand: BD Pharmingen™

Characteristics: Reacts with a 45 kDa transmembrane protein member of the Ig superfamily. CD83 is composed of a single V-type Ig extracellular domain with a C-terminal cytoplasmic tail. CD83 is found mainly on follicular dendritic cells, circulating dendritic cells, interdigitating dendritic cells in lymphoid tissues, in vitro-generated dendritic cells and thymic dendritic cells. However, its expression is not restricted to dendritic cells. CD83 is also expressed on some germinal center B cells and some lymphoblastoid cell lines. Although its function is not known, it may play a role in cell-cell interaction during antigen presentation. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of cultured dendritic cells from human peripheral blood monocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD83 - Purified - Clone HB15e - Isotype Mouse IgG1, κ - Reactivity Hu - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: HB15e

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C.

References for anti-CD83 antibody (ABIN2689416)

Hart: "Dendritic cells: unique leukocyte populations which control the primary immune response." in: Blood, Vol. 90, Issue 9, pp. 3245-87, (1997) (PubMed).

Summers, Daniel, ODonnell, Hart: "Dendritic cells in synovial fluid of chronic inflammatory arthritis lack CD80 surface expression." in: Clinical and experimental immunology, Vol. 100, Issue 1, pp. 81-9, (1995) (PubMed).

Zhou, Tedder: "Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 8, pp. 3821-35, (1995) (PubMed).

Target Details for CD83

Target: CD83

Alternative Name: CD83 (CD83 Products)

Synonyms: BL11 antibody, HB15 antibody, CD83 molecule antibody, CD83 antigen antibody, Cd83 antibody, CD83 antibody

Background: Synonyms: HB15