Goat anti-Rat IgG Antibody (HRP)

Catalog No. ABIN2690389

Product Details

Target: IgG

Reactivity: Rat

Host: Goat

Clonality: Polyclonal

Conjugate: HRP

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Purified by Protein A.

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000
ELISA 1:500-2000
IHC-P 1:500-2000
IHC-F 1:500-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C

Expiry Date: 12 months

References

Hou, Shen, Zhao, Liu, Xie, Deng, Feng: "Mechanism of Mitochondrial Connexin43's Protection of the Neurovascular Unit under Acute Cerebral Ischemia-Reperfusion Injury." in: International journal of molecular sciences, Vol. 17, Issue 5, (2016) (PubMed).

Wang, He, Li, Yu, Hu, Wang, Zhang, Du, Du, Yin, Wei, Mulet, Coia, Weng, He, Wu, Li: "A novel nanobody specific for respiratory surfactant protein A has potential for lung targeting." in: International journal of nanomedicine, Vol. 10, pp. 2857-69, (2015) (PubMed).

Wang, Chen: "MicroRNA-19a functions as an oncogenic microRNA in non-small cell lung cancer by targeting the suppressor of cytokine signaling 1 and mediating STAT3 activation." in: International journal of molecular medicine, Vol. 35, Issue 3, pp. 839-46, (2015) (PubMed).

Hu, Cheng, Zhang, Sun: "Construction and evaluation of a live vaccine against Edwardsiella tarda and Vibrio harveyi: laboratory vs. mock field trial." in: Vaccine, Vol. 29, Issue 24, pp. 4081-5, (2011) (PubMed).

Dang, Zhang, Sun: "Edwardsiella tarda DnaJ is a virulence-associated molecular chaperone with immunoprotective potential." in: Fish & shellfish immunology, Vol. 31, Issue 2, pp. 182-8, (2011) (PubMed).

Sun, Liu, Sun: "A multivalent killed whole-cell vaccine induces effective protection against Edwardsiella tarda and Vibrio anguillarum." in: Fish & shellfish immunology, Vol. 31, Issue 4, pp. 595-9, (2011) (PubMed).

Target Details

Target: IgG

Abstract: IgG Products

Target Type: Antibody

Background:

Immunoglobulin G (IgG), is one of the most abundant proteins in serum with normal levels between 8-17 mg/mL in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions, to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.