Gephyrin antibody

Catalog No. ABIN2721814

Product Details anti-Gephyrin Antibody

Target: Gephyrin (GPHN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Gephyrin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Characteristics: Homo sapiens gephyrin (GPHN), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human GPHN (NP_065857) produced in HEK293T cell.

Clone: 3C6

Isotype: IgG2a

Application Details

Application Notes: WB 1:1000~2000, IHC 1:150, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Gephyrin

Target: Gephyrin (GPHN)

Alternative Name: GPHN (GPHN Products)

Synonyms: 5730552E08Rik antibody, AI662856 antibody, BC027112 antibody, C230040D23 antibody, GPH antibody, GPHRYN antibody, geph antibody, Geph antibody, GPHN antibody, GEPH antibody, HKPX1 antibody, gpgb1 antibody, DKFZp459M0825 antibody, gephyrin antibody, gephyrin L homeolog antibody, gephyrin a antibody, Gphn antibody, GPHN antibody, gphn.L antibody, gphna antibody, PTRG_08978 antibody, VDBG_00775 antibody, Tsp_03043 antibody, gphn antibody

Background: This gene encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

Molecular Weight: 83.3 kDa

Gene ID: 10243

NCBI Accession: NM_020806

HGNC: 10243

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development